Article detail · 2024
Effects of Pervari Honey from Türkiye on Proliferation, Oxidative Stress, and Apoptosis of Human Breast Cancer Cells
Journal
Journal of Advanced Research in Natural and Applied SciencesISSN 2757-5195
- Year
- 2024
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Journal of Advanced Research in Natural and Applied Sciences
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Breast cancer is one of the most common causes of deaths worldwide. Major obstacles to treatment have contributed to the increasing popularity of complementary or alternative therapies. Although recent results support the mechanism that honey induces cell death, the full mechanisms are still unknown. This study investigates the potential use of Pervari honey (PH) as an in vitro therapeutic agent in breast cancer. Firstly, the antioxidant capacity and total phenolic content of PH were tested. In addition, MCF-7 and MDA-MB-231 breast cancer cells treated with PH were examined for cell viability, reactive oxygen species production, oxidative deoxyribonucleic acid (DNA) damage, and apoptosis. Our results show that PH treatment decreased cell viability dose-dependently and increased reactive oxygen species (ROS) levels, oxidative DNA damage, and apoptosis rate. The present study suggests that honey is a promising source to produce pharmaceuticals and nutraceuticals for breast cancer therapy.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
8 citations
OpenAlex cited_by_count (cache / database)
14 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies 2026
- Antioxidant capacity, total phenolic content, and in vitro cytotoxic and oxidative effects of the methanol extract of Dunaliella sp. against breast cancer cells 2025
- Antioxidant capacity, total phenolic content and in vitro cytotoxic and oxidative effects of the methanol extract of Dunaliella sp. against breast cancer cells 2025
- Antioxidant capacity, total phenolic content, and in vitro cytotoxic and oxidative effects of the methanol extract of Dunaliella sp. against breast cancer cells 2025
- Antioxidant capacity, total phenolic content, and in vitro cytotoxic and oxidative effects of the methanol extract of Dunaliella sp. against breast cancer cells 2025
- Effect of Iturin A on Oxidative Stress and Immune Response in Breast Cancer Cell Lines 2026
- Redox Imbalance, Oxidative DNA Damage, and Mitochondrial Membrane Depolarization Induced by Pervari Honey in SH-SY5Y Neuroblastoma Cells 2026
- IMD-1 Protects SH-SY5Y Cells Against H2O2-Induced Oxidative Injury Through Modulation of Oxidative Stress, Mitochondrial Bioenergetics, Inflammatory Mediator Release, and Apoptosis-Related Responses 2026
- Effect of Iturin A on Oxidative Stress and Immune Response in Breast Cancer Cell Lines 2026
- LC–HRMS profile and apoptosis-mediated antiproliferative activity of Eastern Türkiye multifloral honey phenolic extracts on PC-3 prostate cancer cells 2026