Article detail · 2025
Cytotoxicity and antibacterial activity of polyhedral oligomeric silsesquioxane modified Ti3C2Tx MXene films
- Year
- 2025
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Scientific Reports
- Catalog match (ISSN) Scientific Reports
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Bioactive antimicrobial films play important roles in various fields, such as biodegradable interfaces, tissue regeneration, and biomedical applications where preventing infection, biocompatibility, and immune rejection are important. In the present study, bioactive POSS-doped Ti 3 C 2 T x MXene filled PLA composite film was prepared using the solution casting method for biomedical applications. The contact angle tests were investigated to reveal the usability of the thin films in biomedical applications. The angle decreased from 85.92° degrees in pure PLA thin films to 72.23° on POSS-doped Ti 3 C 2 T x MXene films. The antibacterial performance, cytotoxicity and cell viability assessments of the prepared films have also been thoroughly investigated. Antibacterial tests revealed that the POSS-doped Ti 3 C 2 T x MXene films effectively inhibited the growth of E. coli and S. aureus by 65.93% and 80.63%, respectively, within 4 h. These inhibition rates were observed as 58.32% and 54.97% for E. coli and S. aureus , respectively, after 24 h. Cytotoxicity assessments demonstrated that PMPs consistently showed higher cell viability due to the combination of POSS and Ti 3 C 2 T x MXene. The obtained results suggest that the POSS-doped Ti 3 C 2 T x MXene film is a promising candidate in cases where bacterial inhibition and high biocompatibility are of critical importance.
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Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
36 citations
OpenAlex cited_by_count (cache / database)
15 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Ti2NTx MXene and Carbon Quantum Dots Modified Chitosan Scaffold for Potential Wound Healing: In Vitro Assessment of Cytotoxicity, Hemocompatibility, Antioxidant, and Antibacterial Properties 2025
- Ti2NTx MXene and Carbon Quantum Dots Modified Chitosan Scaffold for Potential Wound Healing: In Vitro Assessment of Cytotoxicity, Hemocompatibility, Antioxidant, and Antibacterial Properties 2025
- Ti2NTx MXene and Carbon Quantum Dots Modified Chitosan Scaffold for Potential Wound Healing: In Vitro Assessment of Cytotoxicity, Hemocompatibility, Antioxidant, and Antibacterial Properties 2025
- Review: recent developments in 2D MXene-filled bioinspired composites for biomedical applications 2025
- Review: recent developments in 2D MXene-filled bioinspired composites for biomedical applications 2025
- Review: recent developments in 2D MXene-filled bioinspired composites for biomedical applications 2025
- Review: recent developments in 2D MXene-filled bioinspired composites for biomedical applications 2025
- Ti3C2Tx MXene/halloysite nanotube functionalized films for antibacterial applications 2025
- Ti3C2Tx MXene/halloysite nanotube functionalized films for antibacterial applications 2025
- Ti 3 C 2 T x MXene/halloysite nanotube functionalized films for antibacterial applications 2025