Synthesis of Hydroxyapatite/Collagen (HA/COL) Composite Powder Using a Novel Precipitation Technique

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A new biomimetic precipitation technique was developed to synthesize hydroxyapatite/collagen nanocomposites.The componential and morphological properties of nano-composites were investigated.It was revealed that the inorganic phase in the nano-composite was carbonate-substituted hydroxyapatite with low crystallinity.Indeed both characteristic peaks for HA and Col molecule and shifts of the characteristic peaks have indicated on HA-Col bonding.Morphology studies showed that hydroxyapatite particles with the average size of 50 nm were distributed homogeneously in the polymer matrix.According to the TEM micrographs, inorganic particles were needle-like and had regular crystallographic orientation.These results suggest that the hydroxyapatite/collagen nano-composites are promising biomaterials for bone tissue engineering.