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Article detail · 2023

TOTAL ANTIOXIDANT STATUS, ANTIMICROBIAL AND ANTIPROLIFERATIVE POTENTIALS OF VIOLA ODORATA (FRAGRANT VIOLET)

YÖKSİS OpenAlex Open access · diamond SJR Q3 Citations 17 Percentile 82.6% FWCI 1.55
Year
2023
Type
article

Data source split

  • YÖKSİS YÖKSİS article record
  • YÖKSİS venue Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Catalog match (ISSN) Ankara Universitesi Eczacilik Fakultesi Dergisi
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

Abstract

OpenAlex · English

Objective: Plants are preferred for biological effect. It is a natural resource used in the field of alternative medicine due to its biological effect. In our study, the total oxidant status (TOS) and oxidative stress index (OSI) and total antioxidant status (TAS) of Viola odorata L. species were detected. In addition, antimicrobial and antiproliferative effect of species was detected. Material and Method: The some parts of the species were used with the help of a soxhlet equipment, and ethanol was preferred as a solvent. TOS, OSI and TAS capacitiy were detected using Rel Assay kits. Agar dilution method was preferred to determine antimicrobial effect against bacteria and fungi. Lung cancer cell line (A549) was used to find out the antiproliferative effect by MTT assay. Result and Discussion: Consequently, the studies, the TAS capacitiy of V. odorata extract was detected as 6.752±0.139, the TOS capacitiy as 7.886±0.224 and the OSI capacitiy as 0.117±0.001. V. odorata extracts were determined to be influential against standard bacteria at 25-100 μg/ml intensiy and against fungi at 100-200 μg/ml intensiy. It was detected that the antiproliferative effect of V. odorata extract increased depending on the extract intensiy and showed strong effects. Consequently, it has been detected that V. odorata has important biological effects and in the pharmaceutical industry, it can be preferred after certain stages.

Topics

Citations

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17 citations

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Authors

  1. MUHİTTİN DOĞAN
  2. falah saleh mohammed
  3. İMRAN UYSAL OSMANİYE KORKUT ATA ÜNİVERSİTESİ
  4. KAMİL MENCİK
  5. eylem kına
  6. MUSTAFA PEHLİVAN
  7. MUSTAFA SEVİNDİK