Article detail · 2008
Clinical and prognostic features of plasmacytomas A multicenter study of Turkish Oncology Group Sarcoma Working Party
- Year
- 2008
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue American Journal of Hematology
- Catalog match (ISSN) American Journal of Hematology
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
To identify the outcomes of prognostic factors of solitary plasmacytoma mainly treated with local radiotherapy (RT). The data were collected from 80 patients with solitary plasmacytoma (SP). Forty patients (50.0%) received radiotherapy (RT) alone while 38 of them (47.5%) were treated with surgery (S) and RT. The median radiation dose was 46 Gy (range 30-64). The median follow up was 2.41 years (range 0.33-12.33). Ten-year overall survival (OS) and local relapse-free survival (LRFS) were 73% and 94%, respectively. The median progression-free survival (PFS) and multiple myeloma-free survival (MMFS) were 3.5 years and 4.8 years, respectively. On multivariate analyses, the favorable factors were radiotherapy dose of > or =50 Gy and RT + S for PFS and younger age for MMFS. For the patients with medullary plasmacytoma, the favorable factor was younger age for MMFS. RT at > or =50 Gy and RT + S may be favorable prognostic factors on PFS. Younger patients, especially with head-neck lesion and without pre-RT macroscopic tumor, seem to have the best outcome when treated with RT +/- S. Progression to MM remains as the main problem especially for older patients.
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Citations
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69 citations
OpenAlex cited_by_count (cache / database)
4 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- A Review for Solitary Plasmacytoma of Bone and Extramedullary Plasmacytoma 2012
- Solitary Plasmacytoma of the Cecum and the Ascending Colon: Surgical Resection as a Treatment Modality 2015
- Solitary Plasmacytoma of the Cecum and the Ascending Colon Surgical Resection as a Treatment Modality 2015
- Solitary Plasmacytoma in a Patient Presenting with Taste Disturbance 2022