Article detail · 2018
Microwave‐Assisted Synthesis, Antioxidant, and Antimicrobial Evaluation of Piperazine‐Azole‐Fluoroquinolone Based 1,2,4‐Triazole Derivatives
- Year
- 2018
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Journal of Heterocyclic Chemistry
- Catalog match (ISSN) Journal of Heterocyclic Chemistry
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Azole derivatives (10a–f) obtained starting from 1‐(4‐fluorohenyl)piperazine were converted to the corresponding Mannich bases (7a–d, 12a,b, and 16a,b) containing β‐lactame or flouroquinolone core via a one‐pot three‐component reaction. The synthesis of conazole analogues was carried out starting from triazole by three steps. Reactions were carried out under conventional‐mediated and microwave‐mediated conditions. All the newly synthesized compounds were screened for their antimicrobial, antioxidant activity, and most of them displayed good–moderate activity.
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Citations
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24 citations
OpenAlex cited_by_count (cache / database)
22 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- 1,2,4-Triazole-derived oxime ether derivatives: Synthesis, characterization, in vitro tyrosinase inhibition properties and in silico studies 2025
- Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids 2022
- Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids 2022
- Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids 2022
- Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H-1,2,4-Triazole Ring 2022
- Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1 H ‐1,2,4‐Triazole Ring 2022
- Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H‐1,2,4‐Triazole Ring 2022
- Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H-1,2,4-Triazole Ring 2022
- 1,2,4-Triazole-derived oxime ether derivatives: Synthesis, characterization, in vitro tyrosinase inhibition properties and in silico studies 2025
- Microwave-assisted Synthesis of Novel Mannich Base and Conazole Derivatives Containing Biologically Active Pharmacological Groups 2021