Article detail · 2015 · article
Increased Platelet Distribution Width Is Associated With Severity of Coronary Artery Disease in Patients With Acute Coronary Syndrome
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- YÖKSİSYÖKSİS article record
- YÖKSİS venueAngiology
- Catalog match (ISSN)Angiology
- OpenAlexOpenAlex enrichment (abstract, citations, topics)
- Semantic Scholarcitation count (not merged with OpenAlex)
Abstract
Platelet activation plays a pivotal role in acute coronary syndrome (ACS). We investigated the relationship between platelet distribution width (PDW) and severity of coronary artery disease (CAD) in patients with ACS. A total of 502 patients with ACS were enrolled. High (n = 151) and low PDW (n = 351) groups were defined as patients having values in the third tertile (>17%) and lower 2 tertiles (≤17%). There were significantly higher Gensini score (44 [10-168] vs. 36 [2-132], P < .001), and neutrophil-lymphocyte ratio (3.1 [0.8-12.4] vs. .2.5 [0.3-13], P = .012) and baseline platelet counts were significantly lower (220 [61-623] vs. 233 [79-644] 10(3)/mm3, P = .022) in the high PDW group. The variables PDW >17%, diabetes mellitus, and myocardial infarction were found to be associated with high Gensini score (odds ratio [OR]: 1.91, 95% confidence interval [CI]: 1.27-2.88, P = .002; OR: 2.85, 95% CI: 1.91-4.25, P < .001; OR: 2.67, 95% CI:1.74-4.1, P < .001, respectively). An increased PDW (>17%) is associated with severity of CAD in patients with ACS.
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Citations
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60citationsOpenAlex · cited_by_count (cache / database)
26 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
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- 2020 Association between Hemogram Parameters and Coronary Collateral Development in Subjects with Non-ST-Elevation Myocardial InfarctionCitations 17 · OpenAlex
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- 2020 Association between Hemogram Parameters and Coronary Collateral Development in Subjects with Non-ST-Elevation Myocardial InfarctionCitations 17 · OpenAlex
- 2016 Relation of platelet indices to severity of coronary artery disease in patients undergoing primary percutaneous coronary interventionCitations 16 · OpenAlex