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Article detail · 2022

Prasugrel-related hepatotoxicity

Pakistan Medical Association

YÖKSİS OpenAlex Open access · gold SJR Q4 JCR Q4 Citations 3 Percentile 64.2% FWCI 0.46
Year
2022
ISSN
0030-9982
Type
article

Data source split

  • YÖKSİS YÖKSİS article record
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

Abstract

English (OpenAlex)

Prasugrel is usually preferred over Clopidogrel to reduce the risk of recurrent coronary thrombosis in patients who undergo percutaneous coronary interventions during an acute coronary syndrome owing to its more potent and more rapid antithrombotic activation. Little is known about Prasugrel-induced hepatotoxicity, although mild-to-moderate alanine transaminase (ALT) and gamma glutamyl transpeptidase (GGT) elevations have been noticed in post-marketing surveillance. Herein, we report the case of a patient with Prasugrel-related hepatotoxicity that was reverted after switching from Prasugrel to Ticagrelor.

Topics

  • Antiplatelet Therapy and Cardiovascular Diseases
  • Heparin-Induced Thrombocytopenia and Thrombosis

Primary topic Antiplatelet Therapy and Cardiovascular Diseases

Authors

  1. ZEKİ DOĞAN
  2. MUSTAFA YURTDAŞ
  3. GÖKHAN BEKTAŞOĞLU İSTANBUL ATLAS ÜNİVERSİTESİ