Article detail · 2015
Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution
Journal
LIGHT-SCIENCE & APPLICATIONSISSN 2047-7538
The ISSN points to another catalog journal; the name is from the YÖKSİS record.
- Year
- 2015
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue LIGHT-SCIENCE & APPLICATIONS
- Catalog match (ISSN) Light: Science and Applications
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Abstract In this paper, an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing. The samples are illuminated by a nearly coherent illumination system, where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor. To increase the resolution, a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene, with small planar displacements. Displacements are resolved by a hybrid approach: (i) alignment of the LR images by a fast feature-based registration method, and (ii) fine adjustment of the sub-pixel information using a continuous optimization approach designed to find the global optimum solution. Numerical method for phase-retrieval is applied to decode the signal and reconstruct the morphological details of the analyzed sample. The presented approach was evaluated with various biological samples including sperm and platelets, whose dimensions are in the order of a few microns. The obtained results demonstrate a spatial resolution of 1.55 μm on a field-of-view of ≈30 mm2.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
133 citations
OpenAlex cited_by_count (cache / database)
22 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Photonic crystals: emerging biosensors and their promise for point-of-care applications 2017
- Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings 2016
- Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring 2016
- Current trends and challenges in point-of-care urinalysis of biomarkers in trace amounts 2022
- Current trends and challenges in point-of-care urinalysis of biomarkers in trace amounts 2022
- A Novel On‐Chip Method for Differential Extraction of Sperm in Forensic Cases 2018
- A Novel On‐Chip Method for Differential Extraction of Sperm in Forensic Cases 2018
- A Novel On-Chip Method for Differential Extraction of Sperm in Forensic Cases 2018
- Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications 2016
- Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications 2016