The Effect of Serum and Follicular Fluid Fetuin-B Levels on In Vitro Fertilization Treatment

English (OpenAlex)

Objective: The aim of this study was to investigate the difference between fetuin-B levels in serum and follicular fluid of patients with unexplained infertility, polycystic ovary syndrome (PCOS) and poor ovarian response undergoing In vitro fertilization (IVF) treatment and to investigate the effect of fetuin-B levels on oocyte quality, embryo number and clinical pregnancy. Material and Method: In this prospective study, women with unexplained infertility (n=25), women with polycystic ovary syndrome (n=25), and women with poor ovarian response (n=25) who were diagnosed with infertility and started IVF treatment were included. Fetuin-B levels in serum and follicular fluid of the groups were tested using the ELISA method. In addition, the effect of the difference in fetuin-B levels between the groups on reproductive success was investigated. Results: The differences between the distributions of fetuin-B levels measured in follicular fluid were not statistically significant in all three groups (p>0.05). On the other hand, the fetuin-B level measured in serum was statistically significantly higher in the PCOS group than in the bad ovary group (p