Article detail · 2021
Investigation of antibiotic susceptibilities of Brucella Strains isolated from various clinical samples in eastern Turkey
Journal
European Journal of Medical ResearchISSN 2047-783X
The ISSN points to another catalog journal; the name is from the YÖKSİS record.
- Year
- 2021
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue European Journal of Medical Research
- Catalog match (ISSN) European Journal of Medical Research (discontinued)
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Abstract Background Brucellosis is a worldwide zoonotic disease that causes serious public health problems. This study aimed to identify Brucella strains isolated from various clinical samples by conventional and molecular methods and to determine antimicrobial susceptibilities against doxycycline (DOX), streptomycin (STR), ciprofloxacin (CIP) and rifampicin (RIF) by the gradient strip (E test) test method. Methods A total of 87 Brucella strains isolated from various clinical specimens between 2004 and 2018 were included in this study. While four of the 87 strains included in the study were identified only at the genus level, the remaining 83 strains were identified at the species level by the Real-Time Multiplex PCR (M-RT-PCR) method and conventional methods were used for biotyping. Results According to molecular identification results, 83 strains were identified as B. melitensis by the M-RT-PCR method, with 82 strains identified as Brucella melitensis biovar (bv) 3 and one as B. melitensis bv 1 according to the conventional biotyping method. Among the antibiotics studied, CIP was found to be the most active agent according to the minimum inhibitory concentrations (MIC)90 values. This was followed by DOX and STR, respectively. While all of the isolates were sensitive to CIP, DOX and STR, 18 (20.7%) strains were found to be moderately susceptible to RIF, with the highest values of MIC50 and MIC90. Conclusions In our study, all strains were identified as B. melitensis. DOX, STR, CIP and RIF used in the treatment of brucellosis were found to be effective.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
18 citations
OpenAlex cited_by_count (cache / database)
14 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The Canonical Brucella Species-Host Dependency is Changing, However, the Antibiotic Susceptibility Profiles Remain Unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged. 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023