Article detail · 2025 · article
Radiopharmaceutical properties of hydroxyapatite smaller than 50nm produced from eggshell and labeled with 99mTc and its biodistribution in rabbits
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- YÖKSİSYÖKSİS article record
- YÖKSİS venueHellenic Journal of Nuclear Medicine
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Abstract
OBJECTIVE: Tc) and the in vivo distribution of this molecule in rabbits. MATERIALS AND METHODS: Tc radionuclide, stability of the labeled product, and biodistribution profile in rabbits were investigated. RESULTS: Tc-HANP showed accumulation in bone tissue in the second hour. CONCLUSION: Technetium-99m-HANP nanoradiopharmaceuticals with sizes less than 50 nanometers (20-31nm) showed high uptake in bone tissue in rabbits. Therefore, HANP can be developed as imaging radiopharmaceuticals in bone tissue and bone cancers.
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