Assessment of Exercise Stress Test Parameters in Patients with Erectile Dysfunction

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Objective: Erectile dysfunction (ED) has a significant impact on quality of life, given its high prevalence and association with cardiovascular diseases.In the present study, we aimed to evaluate exercise treadmill parameters in patients with ED.Methods: A total of 178 patients who were admitted to the cardiology clinic was enrolled in the study.Patients were divided into two groups according to their International Index of Erectile Function-5 (IIEF-5) score.Exercise time, maximum heart rate (HR), resting HR, chronotropic index (CI), HR recovery at one minute (HRR1) and two minutes (HRR2) were evaluated for each patient.Results: Subjects with ED were older, had similar rates of diabetes mellitus and hypertension compared to control group.Exercise time was longer and peak HR was higher in patients with ED compared to the healthy counterparts [556.00 (61) sec.vs 575.5 (84) sec.p=0.025, and 156.00 (13) bpm vs 160.50 (11) bpm p=0.001, respectively].We did not find statistically significant differences with respect to resting HR, HRR1, HRR2, CI, maximum systolic and diastolic blood pressure, or rate pressure product between two groups.IIEF-5 score was negatively correlated with age (r=-0.54,p=<0.001),TC (r=-0.32,p=<0.001),LDL-C (r=-0.34,p=<0.001),TG (r=-0.17,p=0.02) and positively correlated with exercise time (r=0.19,p=0.01) and maximal HR (r=0.24,p=0.001).Prevalence of abnormal HRR1 values was significantly higher in study group (n=29, 23.6%) compared to control group (n=6, 10.9 %) (p=004).According to Quade's ANCOVA results, exercise time and maximal Amaç: Bu çalışmada erektil disfonksiyonlu (ED) hastalarda treadmill egzersiz testi parametrelerini incelemeyi amaçladık.Yöntemler: Kardiyoloji polikliniğine başvuran 178 hastaya Uluslararası Erektil İşlev Formu-5 (UAEİF-5) doldurtuldu.Sonuçlara göre hastalar iki gruba ayrıldı.Hastaların egzersiz zamanı, maksimum kalp hızı (KH), istirahat KH, kronotropik indeksi (Kİ), birinci ve ikinci dakikadaki KH toparlanma indeksleri (KHTİ 1 ve KHTİ 2) hesaplandı.Bulgular: ED'si olan hastalar daha yaşlı idi, diyabet ve hipertansiyon açısından her iki grup arasında fark gözlenmedi.Egzersiz zamanı ED'li hastalarda kontrol grubuna göre daha uzundu ve maksimum KH daha yüksekti [556,00 (61) dk ile 575,5 (84) dk p=0,025 ve 156,00 (13) vuru/dk ile 160,50 (11) vuru/dk p=0,001].İstirahat KH, KHTİ 1, KHTİ 2 ve Kİ açısından gruplar arasında fark saptanmadı.UAEİF-5 skoru yaş (r=-0,54, p=<0,001), total kolesterol (r=-0,32, p=<0,001), LDL-K (r=-0,34, p=<0,001) ve TG (r=-0,17, p=0,02) ile pozitif, egzersiz süresi (r=0,19, p=0,01) ve maksimum KH (r=0,24, p=0,001) ile negatif korrelasyon gösterdi.Anormal KHTİ 1 değerleri çalışma grubunda kontrol grubuna göre anlamlı olarak yüksek bulundu (sırası ile, n=29, %23,6 ile n=6, %10,9, p=0,04).Quade ANCOVA sonuçlarına göre yaş kovaryant olarak alındığında egzersiz zamanı ve maksimum KH iki grup arasında farklı bulunmadı (sırası ile, F=1,032 p=0,311 and F=1,264, p=0,262).