Article detail · 2014
Lipid Peroxidation Markers in Children with Anxiety Disorders and Their Diagnostic Implications
- Year
- 2014
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Redox Report
- Catalog match (ISSN) Redox Report
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
OBJECTIVE: Numerous factors, including genetic, neurobiological, neurochemical, and psychological factors, are thought to be involved in the development of anxiety disorders. The latest findings show that the pathophysiology of anxiety disorders might be associated with oxidative stress and lipid peroxidation; however, no studies have so far investigated lipid peroxidation markers in children with anxiety disorders. Serum levels of lipid hydroperoxide (LOOH) are a reliable marker of lipid peroxidation. Paraoxonase and arylesterase are two enzymes that protect against such peroxidation, and might also be diagnostic markers. In this study, we investigated whether there are associations between anxiety disorders and lipid peroxidation markers in children, and assessed the diagnostic performance of these markers. METHODS: The study group consisted of 37 patients (children and adolescents) with anxiety disorders. A control group, matched for age and gender, was composed of 36 healthy subjects. Venous blood samples were collected, and LOOH levels and paraoxonase and arylesterase activity were measured. RESULTS: LOOH levels were significantly higher in the anxiety disorders group than in the control group. There were no significant differences in paraoxonase or arylesterase activities between the patient and the control groups. DISCUSSION: Lipid peroxidation or oxidative damage might play a role in the aetiopathogenesis of anxiety disorders. LOOH may be a potential biological marker for anxiety disorders in children.
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Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
20 citations
OpenAlex cited_by_count (cache / database)
16 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Altered lipid peroxidation markers are related to post traumatic stress disorder PTSD and not trauma itself in earthquake survivors 2016
- Altered lipid peroxidation markers are related to post traumatic stress disorder PTSD and not trauma itself in earthquake survivors 2016
- Altered lipid peroxidation markers are related to post traumatic stress disorder PTSD and not trauma itself in earthquake survivors 2016
- Altered lipid peroxidation markers are related to post traumatic stress disorder PTSD and not trauma itself in earthquake survivors 2015
- Altered lipid peroxidation markers are related to post traumatic stress disorder PTSD and not trauma itself in earthquake survivors 2015
- Decreased serum paraoxonase and arylesterase activities in patients with rosacea 2015
- Investigation of the role of 8 OHdG and oxidative stress in papillary thyroid carcinoma 2015
- Investigation of the role of 8 OHdG and oxidative stress in papillary thyroid carcinoma 2015
- Investigation of the role of 8 OHdG and oxidative stress in papillary thyroid carcinoma 2015
- Investigation of the role of 8 OHdG and oxidative stress in papillary thyroid carcinoma 2015