Phagocytosis and Immune Regulation

BACKGROUND: Cabozantinib inhibits tyrosine kinases, including vascular endothelial growth factor receptors 1, 2, and 3, MET, and AXL, which are implicated in the progression of hepatocellular carcinoma and the development of resistance to sorafenib, the standard initial treatment for advanced disease. This randomized,…

• İRFAN ÇİÇİN

Özet henüz yok.

Özet henüz yok.

• AHMET GÜL
• TEVFİK TAMER ÖNDER

Özet henüz yok.

• TEVFİK TAMER ÖNDER

Özet henüz yok.

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is a cancer of the exocrine pancreas with unmet medical need and is strongly promoted by tumor-associated macrophages (TAM). The presence of TAMs is associated with poor clinical outcome, and their overall role, therefore, appears to be protumorigenic. The "don't eat me…

Type I cells have been defined to be independent of mitochondria for the induction of Fas death receptor-mediated apoptosis, whereas Type II cells are mitochondria-dependent. Knock-out studies in mice show that thymocytes are Type I and liver cells are Type II. We have previously shown that primary human hepatocytes a…

• NESRİN ERKOL

Özet henüz yok.

• NAZMİ VOLKAN ADSAY

BACKGROUND AND PURPOSE: Both necrotic and apoptotic cell death mechanisms are activated after cerebral ischemia. However, whether they are concomitantly active in the same cell or in discrete cell populations is not known. METHODS: We investigated activation of both pathways at the cellular level in mice brains subjec…

• TURGAY DALKARA

Özet henüz yok.

• ALİŞAN YILDIRAN

BACKGROUND: Inflammation is a critical component of tumor progression. Many cancers arise from sites of infection, chronic irritation, and inflammation. It is now becoming clear that the tumour microenvironment, which is largely orchestrated by inflammatory cells, is an essential participant in the neoplastic process,…

• CELALETTİN EROĞLU

BACKGROUND: Inflammation is a critical component of tumor progression. Many cancers arise from sites of infection, chronic irritation, and inflammation. It is now becoming clear that the tumour microenvironment, which is largely orchestrated by inflammatory cells, is an essential participant in the neoplastic process,…

• CELALETTİN EROĞLU