Bioactive Natural Diterpenoids Research

Grayanotoxin is a naturally occurring sodium channel toxin which enters the human food supply by honey made from the pollen and nectar of the plant family Ericaceae in which rhododendron is a genus. Grayanotoxin/mad honey poisoning is a little known, but well studied, cholinergic toxidrome resulting in incapacitating…

• FAİK AHMET AYAZ

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• MURAT TOPBAŞ

Pancreatic cancer is the most lethal malignancy of the gastrointestinal tract. Because of its propensity for early local and distant spread, affected patients possess extremely poor prognosis. Currently applied treatments are not effective enough to eradicate all cancer cells, and minimize their migration. Besides, th…

Grayanotoxins are known to occur in the honey produced from the nectar of Rhododendron ponticum growing on the mountains of the eastern Black Sea region of Turkey and also in Japan, Nepal, Brazil, and some parts of North America and Europe. Two cases of honey intoxication are presented here. Both of the patients exper…

Grayanotoxins are known to occur in honey produced from the nectar of Rhododendrons of the family Ericaceae. Grayanotoxins extracted from honey sample obtained from a patient who experienced severe bradycardia and hypotension after ingesting two tablespoonfuls corresponded to Rhododendron ponticum tetrades. Anaestheti…

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• ESRA AKKOL

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• GÖKHAN ZENGİN

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• HÜSEYİN ŞENOCAK

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• ALİ TİMUÇİN ATAYOĞLU

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• ESRA AKKOL