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Article detail · 2024

The functional role of the pulvinar in discriminating between objective and subjective cognitive impairment in major depressive disorder

Alzheimer's & Dementia: Translational Research & Clinical Interventions

YÖKSİS OpenAlex ISSN 2352-8737 DOI 10.1002/trc2.12450 Citations 6 Open access · gold SJR Q1 JCR Q1

10.1002/trc2.12450

YÖKSİS YÖKSİS article record

OpenAlex OpenAlex enrichment (abstract, citations, topics)

Abstract

OpenAlex record

English (OpenAlex)

INTRODUCTION: Emotionally driven cognitive complaints represent a major diagnostic challenge for clinicians and indicate the importance of objective confirmation of the accuracy of depressive patients' descriptions of their cognitive symptoms. METHODS: We compared cognitive status and structural and functional brain connectivity changes in the pulvinar and hippocampus between patients with total depression and healthy controls. The depressive group was also classified as "amnestic" or "nonamnestic," based on the members' subjective reports concerning their forgetfulness. We then sought to determine whether these patients would differ in terms of objective neuroimaging and cognitive findings. RESULTS: The right pulvinar exhibited altered connectivity in individuals with depression with objective cognitive impairment, a finding which was not apparent in depressive patients with subjective cognitive impairment. DISCUSSION: The pulvinar may play a role in depression-related cognitive impairments. Connectivity network changes may differ between objective and subjective cognitive impairment in depression and may play a role in the increased risk of dementia in patients with depression.

OpenAlex enrichment

Topics

  • Functional Brain Connectivity Studies
  • Mental Health Research Topics
  • Treatment of Major Depression

Type: article Functional Brain Connectivity Studies

Index information

WoS (JCR) and Scopus (SJR) quartiles by ISSN and publication year. · 2024

Scopus (SJR) / WoS (JCR)

Alzheimer's and Dementia: Translational Research and Clinical Interventions

Scopus (SJR) Q1 2,146 Year 2024
WoS (JCR) Q1 JIF 6,8 Year 2024

Universities

  • ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ

Authors

  1. BURAK YULUĞ
  2. SEVİLAY AYYILDIZ
  3. DİLA SAYMAN ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ
  4. RAMAZAN KARACA
  5. Lütfiye İpek
  6. ŞEYDA ÇANKAYA ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ
  7. CEYHUN SAYMAN
  8. ALİ BEHRAM SALAR
  9. BEHÇET AYYILDIZ
  10. AHMET ÖZŞİMŞEK ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ
  11. Nilay Yağcı
  12. ECE ÖZDEMİR ÖKTEM
  13. HALİL AZİZ VELİOĞLU
  14. LÜTFÜ HANOĞLU
  15. Christian Mukata