4 5 Diarylisoxazol 3 carboxylic acids A new class of leukotriene biosynthesis inhibitors potentially targeting 5 lipoxygenase activating protein FLAP

Yerel katalogda bu makaleye atıf yapan 52 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).

1. 2018 Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesisAtıf 67 · OpenAlex
2. 2018 Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agentsAtıf 46 · OpenAlex
3. 2016 BRP 187 A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5 lipoxygenase 5 lipoxygenase activating protein FLAP complex assemblyAtıf 45 · OpenAlex
4. 2016 BRP 187 A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5 lipoxygenase 5 lipoxygenase activating protein FLAP complex assemblyAtıf 45 · OpenAlex
5. 2019 Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitorsAtıf 41 · OpenAlex
6. 2018 Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7Atıf 34 · OpenAlex
7. 2020 Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivityAtıf 27 · OpenAlex
8. 2018 Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammationAtıf 25 · OpenAlex
9. 2018 Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammationAtıf 24 · OpenAlex
10. 2022 Novel potent benzimidazole-based microsomal prostaglandin E2 Synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthaseAtıf 20 · OpenAlex