BRP 187 A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5 lipoxygenase 5 lipoxygenase activating protein FLAP complex assembly

Yerel katalogda bu makaleye atıf yapan 45 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).

1. 2018 Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesisAtıf 67 · OpenAlex
2. 2018 Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7Atıf 34 · OpenAlex
3. 2020 Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivityAtıf 27 · OpenAlex
4. 2022 Novel potent benzimidazole-based microsomal prostaglandin E2 Synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthaseAtıf 20 · OpenAlex
5. 2022 Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthaseAtıf 20 · OpenAlex
6. 2022 Novel potent benzimidazole-based microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C-4 synthaseAtıf 20 · OpenAlex
7. 2022 Novel potent benzimidazole-based microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C-4 synthaseAtıf 20 · OpenAlex
8. 2020 Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocolAtıf 12 · OpenAlex
9. 2020 Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening ProtocolAtıf 12 · OpenAlex
10. 2021 Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacyAtıf 11 · OpenAlex