Caveolin-1 and cellular processes

Bernard-Soulier syndrome (BSS) is a rare autosomal recessive bleeding disorder characterized by defects of the GPIb-IX-V complex, a platelet receptor for von Willebrand factor (VWF). Most of the mutations identified in the genes encoding for the GP1BA (GPIbα), GP1BB (GPIbβ), and GP9 (GPIX) subunits prevent expression…

• HÜSEYİN TOKGÖZ

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• ADNAN YÜKSEL

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• GÖZDE YEŞİL SAYIN
• YASEMİN ALANAY

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• GÖZDE YEŞİL SAYIN
• YASEMİN ALANAY

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• YASEMİN ALANAY

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• YASEMİN ALANAY

Objective Serrated colorectal cancer (CRC) accounts for approximately 25% of cases and includes tumours that are among the most treatment resistant and with worst outcomes. This CRC subtype is associated with activating mutations in the mitogen-activated kinase pathway gene, BRAF, and epigenetic modifications termed t…

To the editor: Integrins constitute the major and largest cell adhesion receptor family. These heterodimers undergo dramatic allosteric conformational changes in response to various activation signals acting on their beta integrin subunit tails.[1][1] In hematopoietic cells, these events are

• GÜLSÜM İCLAL BAYHAN

Here, we investigated the possible predictive value of stromal caveolin-1 (Cav-1) as a candidate biomarker for clinical outcome in triple negative (TN) breast cancer patients. A cohort of 85 TN breast cancer patients was available, with the necessary annotation and nearly 12 years of follow-up data. Our primary outcom…

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• FATİH ÖZALTIN
• SEVCAN AZİME BAKKALOĞLU EZGÜ

BACKGROUND: Endothelial cells are important in initiating adhesive processes between circulating cells and extracellular structures and changes in their distribution are believed to be important in many pathologic conditions. Since little is known about the detailed distribution of adhesion molecules in human endothel…

• IŞINSU KUZU

BACKGROUND: Caveolin-1 is the main component of caveolae membrane structures and has different roles during tumorigenesis in different cancer types with varying expression profiles, indicating that the role of caveolin-1 varies according to tumor type. In this study, we investigated the role and expression of caveolin…

• DENİZ NART
• ÖZGÜL SAĞOL