Hemostasis and retained surgical items

Hemocompatibility of blood-contacting biomaterials is one of the most important criteria for their successful in vivo applicability. Thus, extensive in vitro analyses according to ISO 10993-4 are required prior to clinical applications. In this review, we summarize essential aspects regarding the evaluation of the hem…

• MELTEM AVCI ADALI

Ankaferd Blood Stopper (ABS), a standardized mixture of five plants, has been used historically as a haemostatic agent but its mechanism of action remains unknown. This study investigated the in vitro effects of ABS on haemostatic parameters. When added to plasma or serum, ABS induced the very rapid formation of a pro…

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• MELTEM AVCI ADALI

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• GÖKÇEN YAŞAYAN

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• ALİ AKPEK
• AYÇA BAL ÖZTÜRK
• GÖKÇEN YAŞAYAN
• SEDA NUR TOPKAYA ÇETİN

Vascular endothelial cell growth factor (VEGF) has strong stimulating effects on vascularization. Though very potent, VEGF is rapidly degraded due to its short half-life and when administrated by uncontrolled and nonspecific methods; however, its systemic administration in large doses can cause harmful side effects. C…

• YAŞAR MURAT ELÇİN

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• ALI ZARRABI

Woodward, Stephen C. MC, USAR; Herrmann, John B. MC, USAR; Cameron, John L. MC, USAR; Brandes, George B.S.; J. Pulaski, Col. Edwin MC, USA; Leonard, Fred Ph.D. Author Information

The aim was to evaluate the efficacy and safety of two recombinant factor VIIa (rFVIIa) dose regimens for treating haemarthroses in patients with congenital haemophilia A or B and inhibitors. This was a multicentre, randomised, cross-over, double-blind trial. Patients were randomly allocated to treat a first joint ble…

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