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OpenAlex konusu

Receptor Mechanisms and Signaling

Bu sayfa OpenAlex konu etiketine göre çalışmaları ve o konuda görünen akademisyenleri listeler. YÖKSİS temel alan / yan dal değildir.

OpenAlex 1.519 eser 44 yazar konusu

Çalışmalar

1.519 eser

  1. Dopamine release in the nucleus accumbens core signals perceived saliency 2021
    OpenAlex üst %1 OpenAlex 99.4%

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  2. Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. 1992
    OpenAlex üst %10 OpenAlex 95.8%

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  3. Community guidelines for GPCR ligand bias: IUPHAR review 32 2022
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %1 OpenAlex 99.6%

    GPCRs modulate a plethora of physiological processes and mediate the effects of one-third of FDA-approved drugs. Depending on which ligand activates a receptor, it can engage different intracellular transducers. This 'biased signalling' paradigm requires that we now characterize physiological signalling not just by re…

  4. Reverse physiology in Drosophila: identification of a novel allatostatin-like neuropeptide and its cognate receptor structurally related to the mammalian somatostatin/galanin/opioid receptor family 1999
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 95.1%

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  5. Spontaneous and evoked glutamate release activates two populations of NMDA receptors with limited overlap 2008
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 98.2%

    In a synapse, spontaneous and action-potential-driven neurotransmitter release is assumed to activate the same set of postsynaptic receptors. Here, we tested this assumption using (+)-5-methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate (MK-801), a well characterized use-dependent blocker of NMDA rec…

  6. Plasma serotonin levels and the platelet serotonin transporter 2007
    YÖKSİS SJR Q1 JCR Q1 OpenAlex 88.4%

    Serotonin (5HT) is a platelet-stored vasoconstrictor. Altered concentrations of circulating 5HT are implicated in several pathologic conditions, including hypertension. The actions of 5HT are mediated by different types of receptors and terminated by a single 5HT transporter (SERT). Therefore, SERT is a major mechanis…

  7. Allostery and population shift in drug discovery 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 98.4%

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  8. Allostery and population shift in drug discovery 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 98.4%

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  9. The Effect of Diabetes on Expression of β1-,β2-, and β3-Adrenoreceptors in Rat Hearts 2001
    YÖKSİS SJR Q1 JCR Q1 OpenAlex 89.0%

    Diabetic hearts exhibit decreased responsiveness to stimulation by beta-adrenoreceptor (beta-AR) agonists. This decrease in activity may be due to changes in expression and/or signaling of beta-AR. Recently we showed that right atrial strips from 14-week streptozotocin (STZ)-induced diabetic rat hearts exhibit decreas…

  10. Nicotine up regulates 4 2 nicotinic receptors and ER exit sites via stoichiometry dependent chaperoning 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 97.0%

    The up-regulation of α4β2* nicotinic acetylcholine receptors (nAChRs) by chronic nicotine is a cell-delimited process and may be necessary and sufficient for the initial events of nicotine dependence. Clinical literature documents an inverse relationship between a person's history of tobacco use and his or her suscept…

  11. The regional and cellular expression profile of the melatonin receptor MT1 in the central dopaminergic system 2005
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 92.3%

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  12. Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry Implications for Drug Discovery 2009
    YÖKSİS SJR Q1 JCR Q1 OpenAlex üst %10 OpenAlex 97.2%

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Akademisyenler

44 akademisyen