Forensic and Genetic Research

Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30,000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to t…

• CAN ALKAN

We present a DNA library preparation method that has allowed us to reconstruct a high-coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The quality of this genome allows a direct estimation of Denisovan heterozygosity indicating that genetic diversity in these archaic hominins was extr…

• CAN ALKAN

Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals i…

• CAN ALKAN

We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and over 50 000 years carry C-->T and G-->A substitutions. These substitutions can reach high proportions among the molecules amplified and are due to the occurrence of modified deoxycytidine resi…

• MUZAFFER POLAT

Abstract The determination of age at death is an important part of physical and forensic anthropology. Techniques now in use vary from direct observation of a bone to microscopic examination of a given segment. This study introduces the sternal end of the rib as a new site for age estimation by direct observation. The…

The complete genome sequences of an indigenous hunter-gatherer from Namibia's Kalahari Desert and of a Bantu from South Africa are presented in this issue, together with protein-coding regions from three other hunter-gatherer groups from the Kalahari. Analysis of genetic variance in what is probably the oldest known m…

• CAN ALKAN

While the pubic symphysis and intracortical morphometry have provided successful results in estimating age at death, other methods and sites in the skeleton are needed to improve the accuracy of age estimation. This research is an attempt to develop a new age-determination technique by using the sternal extremity of t…

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• GÖKNUR KALKAN

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• GÖKNUR KALKAN

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• ALİŞAN YILDIRAN

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• HÜSEYİN ÇAKSEN

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• NESLİHAN KARACA