Hydrogels: synthesis, properties, applications

Large hydrophobic monomers stearyl methacrylate (C18) and dococyl acrylate (C22) could be copolymerized with the hydrophilic monomer acrylamide in a micellar solution of sodium dodecyl sulfate (SDS). This was achieved by the addition of salt (NaCl) into the reaction solution. Salt leads to micellar growth and, hence,…

• DENİZ CEYLAN

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• SEVİL DİNÇER İŞOĞLU

Abstract Chitosan and poly(vinyl alcohol) (PVA) were used to form a semi‐interpenetrating polymeric network with glutaraldehyde as the cross‐linker. The molecular weight and degree of deacetylation of the chitosan were 612 kDa and 72 %, respectively. The chemical bonds formed by the cross‐linking reaction and transiti…

• MAHİR TURHAN

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• SEMA EKİCİ

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• ÖZGÜR ÖZAY

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• NURETTİN ŞAHİNER

Injectable hydrogels have received considerable interest in the biomedical field due to their potential applications in minimally invasive local drug delivery, more precise implantation, and site-specific drug delivery into poorly reachable tissue sites and into interface tissues, where wound healing takes a long time…

• NERMİN SEDA KEHR

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• CAN ERKEY
• ZEYNEP ÜLKER DEMİR

Over the past 18 years we have been deeply involved with the synthesis and applications of stimuli-responsive polymer systems, especially polymer-biomolecule conjugates. This article summarizes our work with one of these conjugate systems, specifically polymer-protein conjugates. We include conjugates prepared by rand…

Nanoparticles consisting of human therapeutic drugs are suggested as a promising strategy for targeted and localized drug delivery to tumor cells. In this study, 5‐fluorouracil (5‐FU) encapsulated chitosan nanoparticles were prepared in order to investigate potentials of localized drug delivery for tumor environment d…

• MEHLİKA PULAT

Nanoparticles consisting of human therapeutic drugs are suggested as a promising strategy for targeted and localized drug delivery to tumor cells. In this study, 5‐fluorouracil (5‐FU) encapsulated chitosan nanoparticles were prepared in order to investigate potentials of localized drug delivery for tumor environment d…

A promising strategy to design synthetic hydrogels with the ability to self-heal is to substitute the covalently cross-linked polymer chains by supramolecular ones. Although supramolecular hydrogels generally exhibit rapid self-healing without the need for any stimulus, they suffer from low mechanical strength which p…

• ÜMİT GÜLYÜZ