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OpenAlex konusu

Genomics and Chromatin Dynamics

Bu sayfa OpenAlex konu etiketine göre çalışmaları ve o konuda görünen akademisyenleri listeler. YÖKSİS temel alan / yan dal değildir.

OpenAlex 587 eser 23 yazar konusu

Çalışmalar

587 eser

  1. Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions 2015
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  2. Active genes are tri methylated at K4 of histone H3 2002
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  3. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation mediated by SAGA associated Ubp8 2003
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    Gene activation and repression regulated by acetylation and deacetylation represent a paradigm for the function of histone modifications. We provide evidence that, in contrast, histone H2B monoubiquitylation and its deubiquitylation are both involved in gene activation. Substitution of the H2B ubiquitylation site at L…

  4. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression 2004
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  5. Genome wide Chromatin State Transitions Associated with Developmentaland Environmental Cues 2013
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  6. Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues 2013
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  7. Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing 2013
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  8. Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells 2011
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  9. Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9 2016
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  10. Roberts syndrome is caused by mutations in ESCO2 a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion 2005
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  11. Edgetic perturbation models of human inherited disorders 2009
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    Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as 'nodes' and 'edges', respectively. Better understanding of genotype-to-phenotype relationships in human disease will require modeling of h…

  12. Snf1 a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription 2001
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    Modification of histones is an important element in the regulation of gene expression. Previous work suggested a link between acetylation and phosphorylation, but questioned its mechanistic basis. We have purified a histone H3 serine-10 kinase complex from Saccharomyces cerevisiae and have identified its catalytic sub…

Akademisyenler

23 akademisyen