Plant Toxicity and Pharmacological Properties

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Bu bölüm, hayvanlarda yaygın olarak görülen bitkisel kaynaklı zehirlenmeler, mikotoksikozlar ve pestisit zehirlenmelerini kapsamaktadır. Bitkisel kaynaklı zehirlenmeler bölümünde akonitin, aristoloşin, atropin, koniin, kolşisin, roadin ve veratrin gibi toksik maddelerin etki mekanizmaları, klinik belirtileri ve tedavi…

ABSTRACT This study investigated the effects of Prunella vulgaris, Plantago major, and Symphytum officinale on wound healing. Forty-two rats were divided into six groups of seven: Plantago major (PM), Prunella vulgaris (PV), Symphytum officinale (SO), olive oil-beeswax-vitamin E mixture (OBEG), control group (CG), and…

Abstract Objectives Cholestasis, characterized by impaired bile flow and bile accumulation, leads to progressive liver injury largely mediated by oxidative stress. Taurine, a conditionally essential amino acid with antioxidant and cytoprotective properties, may protect against cholestatic liver damage. This study inve…

Bu çalışmada Zile’de bir yaş üstü Akkaraman melezi ırkı koyunlarda (n=138) dışkı bakısı ile akciğer kıl kurdu enfeksiyonunun prevalansı araştırılmıştır. Koyunların %47.8’i akciğer kıl kurdu yönünden pozitif bulunmuştur. Enfekte koyunlarda en sık rastlanan tür Cystocaulus ocreatus olmuş (%72.7), bunu sırasıyla Muelleri…

Abstract Pyrrolizidine alkaloids (PAs) are plant toxins of increasing concern due to their toxic and carcinogenic properties. While the hepatotoxic effects of PAs are well established, limited information is available regarding oxidative stress–related damage in extrahepatic tissues. This study aimed to determine alte…

Monocrotaline (MCT), a plant-derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT-induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemic…

BackgroundTheileriosis, a tick-borne disease caused by Theileria annulata, leads to global economic losses in livestock, emphasizing an urgent need for the identification of new therapeutic agents with alternative mechanisms of action due to rising buparvaquone resistance combined with climate-driven spread. T. annula…

Background: Plant flavonoids are candidate alternatives to ionophores for modulating rumen fermentation, yet the intact glycoside rutin (quercetin-3-O-rutinoside) has received little attention. The objective of this study was to determine whether rutin changes the in vitro ruminal fermentation of total mixed rations (…

Echinophora sibthorpiana Guss. (Apiaceae) is an aromatic plant of considerable ethnobotanical significance, traditionally employed as a flavouring and preservative agent in food and valued for its medicinal properties across the Eastern Mediterranean region, yet its non-volatile phytochemistry and biosafety profile re…

This case series, a re-evaluation of a historical patient cohort after 42 years, provides valuable insights into the natural history of porphyria turcica. It has been confirmed that patient 1 is one of the individuals clinically documented in the landmark cohort study published by Cripps and others in the BJD in 1984.

A method was developed and validated for the simultaneous determination of five macrocyclic lactones (ivermectin, abamectin, doramectin, moxidectin, and eprinomectin) in edible tissues (meat, liver, kidney, and fat) of cattle using a modified QuEChERS extraction procedure. Residue levels were determined by high-perfor…