Eosinophilic Disorders and Syndromes

Kimura hastalığı, subkutan doku ve lenf nodlarını tutan kronik inflamatuar bir hastalıktır. Asya toplumlarında ve genç erişkin erkeklerde daha sık görülür. Kimura hastalığı lenfadenopatisi, genellikle baş-boyun bölgesi lenf nodlarında ağrısız kitle olarak başlangıç yapar. B semptomları nadirdir. LAP yavaşça büyür ve u…

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The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

OBJECTIVE: The Pediatric Quality of Life Inventory™ (PedsQL™) Eosinophilic Esophagitis (EoE) Module is a specialized instrument designed to assess how EoE affects the quality of life in pediatric patients. This study assesses the Turkish cross-cultural adaptation of the 8-12-year-old version. MATERIALS AND METHODS: As…

Background/aim: Chronic myeloid leukemia (CML) is characterized by the Philadelphia chromosome (Ph), which occurs as a result of t(9;22). In 5%-10% of CML cases, variant t(9;22)s are observed. Additionally, while t(9;22) is formed, deletions can be observed in chromosomes 9 and 22. These deletions are observed more fr…

Background Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare eosinophilic lung disease with a high relapse rate and substantial oral corticosteroid (OCS) burden. While mepolizumab, an anti-IL-5 monoclonal antibody, has shown promise in case reports and small series, evidence from long-term follow-up studies r…

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Background: ST-elevation myocardial infarction (STEMI) is most commonly caused by atherosclerotic coronary artery occlusion. In some instances, non-atherosclerotic mechanisms should also be considered. We present a case of a floating thrombus in the aortic root moving in and out of the right coronary ostium, leading t…

Background: Ruxolitinib has been associated with an increased risk of viral infections and tuberculosis reactivation in patients with Philadelphia chromosome-negative myeloproliferative neoplasm. However, data regarding screening practices and prophylactic approaches in routine clinical care remain limited. Objective:…

INTRODUCTION: Myocarditis and perimyocardial syndromes share overlapping features but differ in management. Differentiating them in children presenting with chest pain or palpitations remains difficult, particularly in non-fulminant cases. This study evaluated the diagnostic value of inflammatory biomarkers, especiall…

BACKGROUND: Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening adverse reaction to antipsychotic medications that carries significant diagnostic complexity in its atypical forms, particularly among elderly patients with polypharmacy and multiple comorbidities in whom the classic diagnostic…