Fetal and Pediatric Neurological Disorders

OBJECTIVE: Adrenocorticotropic hormone (ACTH) is an effective treatment for infantile epileptic spasms syndrome (IESS); however, its mechanism of action remains incompletely understood. This study aimed to evaluate ACTH treatment response at the level of protein-protein interactions (PPIs) in patients with confirmed a…

• EDİBE PEMPEGÜL YILDIZ

PURPOSE: To evaluate the incidence of associated structural anomalies, chromosomal/genetic abnormalities, infections and outcomes of fetuses with ventriculomegaly (VM). METHODS: Retrospective multicenter cohort study of 627 pregnancies with fetal VM. VM was classified as mild, moderate, or severe and isolated or non-i…

• BİLGE ÇETİNKAYA DEMİR

BACKGROUND: Myelomeningocele (MMC) is associated with substantial early-life morbidity and mortality. Although hydrocephalus frequently accompanies MMC, its specific relationship to early mortality remains incompletely defined in institutional cohorts. This study aimed to describe early mortality patterns in patients…

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OBJECTIVE: Bell's palsy is the most common form of acute peripheral facial palsy; however, its etiology remains unclear. Environmental and seasonal factors have been suggested as potential triggers, but previous studies have reported conflicting results. The aim of this study was to evaluate the long-term temporal and…

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Iniencephaly is a rare and severe neural tube defect characterized by an occipital bone defect, partial or complete absence of the cervicothoracic vertebrae, and marked hyperextension of the fetal head. Its reported incidence ranges between 0.0001% and 0.01%, with a significantly higher prevalence in female fetuses. I…

Objective: Prenatal diagnosis refers to the detection of fetal and embryonic chromosomal abnormalities during the antenatal period using appropriate methods based on gestational age. This study aimed to identify chromosomal abnormalities in high-risk pregnancies, determine their frequency, and highlight their clinical…

Prenatal diagnosis is essential for allowing for early detection of fetal anomalies.Soft markers, detected during fetal anom aly scans, are of uncertain significance.Most soft markers are transient; their detection can induce psychological distress.The relationship between soft markers, genetic conditions, and materna…

Automated segmentation of multiple anatomical structures in abdominal ultrasound could enhance clinical decision–making by providing consistent quantitative measurements for disease monitoring. However, ultrasound–specific artifacts including speckle noise, low contrast and weak boundaries challenge existing deep lear…

Background/Objectives: In this study, we aimed to evaluate whether neonatal ischemia-modified albumin (IMA) and umbilical venous cord blood gas parameters are associated with antenatal markers of fetal well-being, including the umbilical coiling index (UCI) and umbilical artery (UA) and middle cerebral artery (MCA) Do…