Heme Oxygenase-1 and Carbon Monoxide

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Spontaneous coronary artery dissection (SCAD) is a rare but potentially fatal cause of acute coronary syndrome (ACS), often associated with younger individuals and women without traditional cardiovascular risk factors. Carbon monoxide (CO) poisoning, a known cause of systemic hypoxia, has been implicated in various ca…

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Background: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent episodes of intermittent hypoxia and systemic inflammation. Pannexin-1 (Panx1) is a transmembrane channel involved in ATP release and purinergic signaling and has been implicated in hypoxia-related inflamm…

Aim One of the earliest symptoms of acute carbon monoxide (CO) poisoning is headache. In this study, we aimed to identify cases of CO poisoning by examining SpCO levels as a new vital parameter in patients presenting with headaches, to detect cases that might otherwise be overlooked, and to facilitate early diagnosis…

Hepatic ischemia-reperfusion injury is a major clinical problem associated with liver surgery, trauma, and transplantation, characterized by oxidative stress, inflammation, microcirculatory dysfunction, and apoptosis. Fluoxetine, a selective serotonin reuptake inhibitor, has been reported to exert antioxidant, anti-in…

Objective: Identifying patients at high risk for contrast-induced nephropathy (CIN) is essential for implementing effective preventive strategies. This study aimed to evaluate the predictive value of the total bilirubin-phosphorus ratio (TBPR) for CIN development. Methods: This retrospective, observational study inclu…

Karbonmonoksit (CO) gazı; ciddi hastalıklara veya ölümlere neden olabilen, renksiz, kokusuz, tatsız ve irritan olmayan özellikleri nedeniyle fark edilmesi güç olan bir gazdır ve bu nedenle literatürde sıklıkla “sessiz katil” olarak tanımlanmaktadır (1).

Karbonmonoksit (CO) gazı; ciddi hastalıklara veya ölümlere neden olabilen, renksiz, kokusuz, tatsız ve irritan olmayan özellikleri nedeniyle fark edilmesi güç olan bir gazdır ve bu nedenle literatürde sıklıkla “sessiz katil” olarak tanımlanmaktadır (1).

Modern yaşamın vazgeçilmezi olan kimyasallar, beslenme ve sağlık gibi temel ihtiyaçlarımızın yanı sıra endüstriyel alanlarda kullanımı zorunlu olan maddelerdir. Sanayinin ve teknolojinin hızla gelişmesi, kullanılan kimyasalların çeşitliliğinde artışa neden olmakta ve birçok kimyasalın doğaya salınımını artırmaktadır.…

Aims: To evaluate the association between fractional carboxyhemoglobin (FCOHb) levels and biochemical markers of poisoning severity, and to describe cardiac and neuroimaging findings in a pediatric cohort affected by a single-source mass carbon monoxide (CO) exposure.Methods: This retrospective cross-sectional study i…

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