N-Heterocyclic Carbenes in Organic and Inorganic Chemistry

Lung cancer is among the most common cancers in the world, and current treatments are inadequate due to the development of resistance and serious side effects. This situation brings new therapeutic strategies for cancer treatment. Among these, silver-based N-heterocyclic carbenes (Ag-NHCs) have emerged as promising ca…

In this study, a new series of silver(I) N-heterocyclic carbene (NHC) complexes was rationally designed, synthesized, and systematically evaluated for their anticancer efficacy against breast carcinoma cell lines. Structural diversification was achieved through deliberate ligand modification: complex 1 incorporates a…

A synthesis of four silver(I) complexes was conducted, and they were evaluated for their antimicrobial properties and their ability to inhibit the formation of biofilms. Additionally, their binding affinities to DNA and BSA were investigated. The complexes, chloro[1-isopropyl-3-(3-methylbenzyl)-5,6-dimethylbenzimidazo…

A synthesis of four silver(I) complexes was conducted, and they were evaluated for their antimicrobial properties and their ability to inhibit the formation of biofilms. Additionally, their binding affinities to DNA and BSA were investigated. The complexes, chloro[1-isopropyl-3-(3-methylbenzyl)-5,6-dimethylbenzimidazo…

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This chapter delves into the electrochemical mechanisms that govern organic electrode materials (OEMs) in energy storage systems, highlighting their unique redox behavior and reaction pathways. As a promising alternative to traditional inorganic battery materials, OEMs leverage the redox-active functional groups inher…

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In the search for efficient and stable catalyst systems for organic reactions, N-heterocyclic carbene (NHC) precursors have played an important role in modern organometallic chemistry. Three new benzimidazolium bromide salts were prepared by alkylation of benzimidazole derivatives in this work. The chemical structures…

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using Invitrogen MitoTracker stain. These findings highlight the dual role of 1,10-phenanthroline-linked imidazolium salts as DNA-interacting agents and selective anticancer compounds, paving the way for their further development as targeted chemotherapeutic candidates.

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• NAZAN KALOĞLU