Neuroscience and Neural Engineering

Chemogenetics is a powerful and versatile neuromodulation strategy that enables remote, reversible control of defined cell populations through the use of engineered receptors and pharmacologically inert small-molecule ligands. This review synthesizes the current state of chemogenetic technologies, focusing on Designer…

Background: The involvement of human subjects in the development of biomedical devices presents both ethical and practical challenges. Electroencephalography (EEG) signals exhibit interindividual variability and are subject to fluctuations induced by movement and emotional states. Hence, the fabrication of artificial…

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The design of surface architecture plays a critical role in regulating the physicochemical and biological performance of titanium-based implants. In this study, biomimetic interconnected microchannel surface architecture was fabricated on Ti6Al4V via selective laser melting (SLM). The geometry was generated through an…

PURPOSE: To evaluate the influence of margin level and finish line geometry on the trueness of digital impressions obtained with different intraoral scanners (IOS). MATERIALS AND METHODS: Six maxillary molar crown preparations were designed combining two margin levels (supragingival and subgingival) and three finish l…

The market for transcranial direct current stimulation (tDCS) expands. tDCS is a non-invasive technique that delivers a weak direct electrical current to the scalp via electrodes. It is used for enhancing cognitive functions and mood. Existing research addresses technical aspects; yet, understanding users’ perceptions…

ABSTRACT: The market for transcranial direct current stimulation (tDCS) expands. tDCS is a non-invasive technique that delivers a weak direct electrical current to the scalp via electrodes. It is used for enhancing cognitive functions and mood. Existing research addresses technical aspects; yet, understanding users’ p…

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Abstract Neuroelectronic thin-film implants hold promise for advancing fundamental understanding of the peripheral nervous system and offer potential for targeted treatments using specific stimulation. However, challenges in establishing robust and durable connections to soft and flexible implants limit their widespre…

Organ-on-a-chip (OoC) platforms are a key subclass of microphysiological systems (MPS), designed to mimic the dynamic and physiological properties of native human tissue and organs. These systems have attracted significant attention, particularly following the Food and Drug Administration (FDA) approval of their use i…

The integration process of Large Language Models (LLM) into the healthcare ecosystem is demonstrating a shift from cloud-based systems towards local (on-premise) and opensource Retrieval-Augmented Generation (RAG) architectures due to data privacy regulations such as GDPR and HIPAA. However, these architectures harbor…

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