Synthetic Organic Chemistry Methods

In this study, a new series of silver(I) N-heterocyclic carbene (NHC) complexes was rationally designed, synthesized, and systematically evaluated for their anticancer efficacy against breast carcinoma cell lines. Structural diversification was achieved through deliberate ligand modification: complex 1 incorporates a…

Özet henüz yok.

A photoactive Ru-containing PCL was synthesized via ring-opening polymerization and exhibited light-induced cytotoxicity.

. Collectively, our findings establish biotinylated isoxazole derivatives as potent JAK1-targeting anticancer agents with strong antiproliferative and pro-apoptotic activity, supporting their further development as promising candidates for targeted cancer therapy.

BACKGROUND: Antimicrobial resistance poses a major global health threat, highlighting the urgent need for novel bioactive compounds. Actinomycetes in the phylum Actinomycetota are prolific producers of antimicrobial agents; however, marine-derived strains remain underexplored, despite their ecological diversity and bi…

• ERDAL BEDİR
• GÖKLEM ÜNER
• MUSTAFA ÜNVER KURT
• ATAÇ UZEL

Özet henüz yok.

• AYDIN AKTAŞ

Özet henüz yok.

• AYDIN AKTAŞ
• TUĞBA TAŞKIN TOK

ABSTRACT In this study, we report the synthesis and anticancer activities of new ruthenium complexes with N ‐heterocyclic carbene (NHC) ligands, which are of great significance for drug delivery research. For this reason, 4‐methylsulfonylbenzyl‐substituted benzimidazole‐functionalized Ru(II)NHC complexes were synthesi…

• AZİZ PAŞAHAN
• AYDIN AKTAŞ

Within the scope of this chapter, we provide a quick introduction to a variety of polymerization techniques that transform monomers into copolymers. We also emphasize the distinctive mechanisms that these strategies employ in order to exert control over the structure of polymers. Several different polymerization techn…

Araştırmanın amacı meslek liselerinde görev yapan öğretmenlerin görüşleri doğrultusunda okul yönetimlerinin çevik okul ile kriz yönetimi becerileri arasındaki ilişkinin incelenmesidir. Araştırma ilişkisel tarama modelinde gerçekleştirilmiştir. Araştırmanın örneklemini 2022-2023 eğitim öğretim yılında Kayseri ilindeki…

• UĞUR GEZER

Özet henüz yok.

• NAMIK ÖZDEMİR

Özet henüz yok.

• MİTAT AKKOÇ