Neurofibromatosis and Schwannoma Cases

BACKGROUND: Single-center series remain useful for benchmarking local practice against the published literature. We report a 21-year experience with cranial and spinal meningiomas at one tertiary center in Türkiye. METHODS: We retrospectively reviewed 108 consecutive patients operated for histopathologically confirmed…

RATIONALE: Intraosseous (ectopic) meningiomas are rare extradural tumors arising within the calvarial bone and account for <1% of all meningiomas. Because their imaging appearance may range from osteolytic to sclerotic or mixed patterns, they can mimic primary bone tumors or metastatic lesions and lead to diagnostic u…

BACKGROUND Scalp neurofibromas are uncommon benign peripheral nerve sheath tumors and are typically associated with neurofibromatosis type 1 (NF1). Isolated scalp neurofibromas without NF1 findings are extremely rare, and large lesions with associated calvarial remodeling are even more exceptional. This study presents…

Subependymal giant cell astrocytoma (SEGA) usually arises near the foramen of Monro in patients with tuberous sclerosis complex (TSC). A 14-year-old boy presented with headache and a 6.2 × 5.8 cm extraventricular, cyst-dominant hemispheric lesion containing a mildly enhancing mural nodule. Microsurgical excision was p…

PURPOSE: Biallelic variants in the minor spliceosomal gene RNU4ATAC were successively identified in Taybi-Linder/Microcephalic osteodysplastic primordial dwarfism type I, Roifman, and Lowry-Wood syndromes, which are characterized by variable microcephaly, short stature, neurodevelopmental impairment, skeletal dysplasi…

Özet henüz yok.

Background: Papillary glioneuronal tumor (PGNT) is a rare, World Health Organization (WHO) Grade I mixed glioneuronal neoplasm characterized by the presence of both neuronal and glial elements. It commonly presents with seizures or headaches and has a generally favorable prognosis after gross total resection. Here, we…

Özet henüz yok.

Meningiomas are the most common primary central nervous system tumors and their biological behavior is closely related to histopathological grade and proliferative activity. This study investigated the associations between World Health Organization (WHO) grade, tumor location, mitotic activity, and Ki-67 labeling inde…

Özet henüz yok.

Imaging-based assessment of proliferative and molecular features in adult-type diffuse gliomas may support preoperative tumor characterization. This study evaluated conventional MRI combined with diffusion-weighted imaging (DWI), susceptibility-weighted imaging (SWI), and dynamic susceptibility contrast perfusion-weig…

Abstract Background: Vitamin D has significant effects on neurofibroma development in patients with neurofibromatosis type 1 (NF1). Additionally, vitamin D receptor ( VDR ) gene polymorphisms are associated with various cancers. Aims and Objectives: This study aimed to determine the correlation between NF1 and the ser…