Occupational and environmental lung diseases

For decades, peritoneal metastases (PM) have been regarded as a terminal manifestation of advanced malignancies and managed primarily with palliative intent because of limited sensitivity to systemic therapies. Accumulating clinical, molecular, and immunological evidence now supports the view that PM is not merely an…

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8053 Background: Pleural mesothelioma (PM) is a rare malignancy associated with asbestos exposure and characterized by an aggressive clinical course and poor prognosis. Identifying clinical and biological prognostic markers is of significant clinical importance. Recently, computed tomography (CT) based body compositio…

Aims: This study was designed to investigate the immunohistochemical expression Leucine-Rich Repeat Kinase 2 (Dardarin, LRRK2) and Isthmin-1 (ISM-1) in tumor tissues from patients with MM, alongside a comparison to reactive mesothelial hyperplasia (RMH).Methods: A total of 60 MM and 60 RMH cases who had not received p…

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In modern times, microplastics are common environmental contaminants that are of increasing importance for human health.Ingestion has been traditionally regarded as the dominant route of exposure.However, inhalation of airborne microplastics represents a direct and biologically relevant exposure route to the respirato…

Bu bölüm, afetlerde hava kalitesi bozulmaları ve kimyasal riskleri çevre sağlığı perspektifiyle ele almaktadır. Deprem, sel, yangın, endüstriyel kaza ve nükleer olaylar gibi afetler yalnızca fiziksel yıkıma değil; partikül madde, asbest lifleri, ağır metaller, toksik gazlar, petrol ürünleri ve radyolojik kirleticiler…

Objective: Pericardial effusion is a clinical condition characterized by the pathological accumulation of fluid within the pericardial cavity. It may develop secondary to cardiac, infectious, autoimmune, traumatic, or neoplastic processes. Malignancy-related effusions, particularly in patients with advanced-stage canc…

Giriş: Kanser tedavisi hastalar üzerinde yalnızca klinik değil, ekonomik ve psikososyal yüklerde oluşturmaktadır. Tedavi sürecinde ortaya çıkan ekonomik zorluklar “finansal toksisite” olarak tanımlanmakta ve hastaların yaşam kalitesi ile tedaviye uyumunu etkileyebilen önemli bir sorun olarak değerlendirilmektedir. Bu…

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Aim: This study aimed to retrospectively evaluate the demographic, clinical, and medicolegal characteristics of inhalational exposure cases referred for forensic medical evaluation. It also aimed to examine the distribution of selected clinical findings and medicolegal outcomes according to event type and exposure pat…