Adipokines, Inflammation, and Metabolic Diseases

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• MACİT KALÇIK

OBJECTIVE: Childhood obesity, which continues to rise globally, is associated with inflammation-driven metabolic disturbances and increased cardiometabolic risk. Individual variability in metabolic health—independent of obesity severity—has led to the concept of metabolically healthy obesity (MHO). This study aimed to…

BACKGROUND: The prevalence of diabetes mellitus in the general population has been increasing in recent years, and diabetes-related complications contribute substantially to morbidity, mortality, and healthcare system burden. This study aimed to evaluate the relationship between glycated hemoglobin (HbA1c) levels and…

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AIM: Although short-term cardiometabolic complications are not usually expected in children with metabolically healthy obesity (MHO), subclinical vascular damage may still occur. This study aimed to evaluate Fibroblast Growth Factor 21 (FGF21) levels in children with obesity and their relationship with carotid intima-…

8053 Background: Pleural mesothelioma (PM) is a rare malignancy associated with asbestos exposure and characterized by an aggressive clinical course and poor prognosis. Identifying clinical and biological prognostic markers is of significant clinical importance. Recently, computed tomography (CT) based body compositio…

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Objective: To evaluate six-month changes in hemogram-derived inflammatory indices (neutrophil-tolymphocyte ratio [NLR], systemic immune-inflammation index [SII], systemic inflammation response index [SIRI], and aggregate index of systemic inflammation [AISI]) and their association with glycemic parameters in patients…

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Early risk stratification in acute pulmonary embolism (PE) guides emergency management. Oncostatin M (OSM), an interleukin-6-family cytokine linked to endothelial activation and inflammation, may provide prognostic information complementary to established tools such as the simplified Pulmonary Embolism Severity Index…

Aims: To investigate the relationships between epicardial fat volume (EFV), epicardial fat tissue density (EFD), and pericoronary fat tissue thickness (PCFT) and the coronary calcium score (CS). Epicardial fat tissue, which surrounds the coronary arteries, is thought to be associated with cardiovascular diseases. Meth…

Acute Coronary Syndrome (ACS) is a common cause of emergency department admissions and remains an important contributor to morbidity and mortality. Early identification of disease severity and prognosis is particularly important in young patients with ACS. This study aimed to evaluate the diagnostic and prognostic val…