Circadian rhythm and melatonin

Sleep disorders in children can negatively impact their development and quality of life. While melatonin is commonly used to manage these issues, there are no FDA-approved formulations specifically designed for children, and traditional tablet forms can be challenging for these patients. This study aims to develop a p…

• MERVE NENNİ

This study aimed to examine the relationships between circadian preferences and physiological and psychological stress responses, while also considering the roles of gender, healthy eating habits and regular exercise habits. To achieve this, a two-stage quantitative design was used. In the first stage, data were colle…

This study examined the effects of a two-week 16:8 time-restricted feeding protocol on exercise-induced heart rate responses in professional football players. Participants assigned to the time-restricted feeding group followed the dietary intervention for two consecutive weeks, and adherence to the protocol was monito…

This study aims to investigate the radioprotective effects of melatonin (MEL) against oxidative damage that may be caused by flattening filter (FF) and flattening filter-free (FFF) beam in the cerebrum and cerebellum of rat using various genetic markers. Forty female Wistar albino rats were randomly assigned to five g…

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Triple-negative breast cancer (TNBC) is a distinct molecular subtype of breast cancer, characterized by high mortality and metastasis. Indoleamine 2,3-dioxygenase (IDO) is a highly expressed enzyme in cancer cells that contributes to immunosuppression. The IDO inhibition has been widely used in cancer immunotherapy. I…

OBJECTIVE: This experimental rat study aims to investigate the preventive role of melatonin in potential neurodegenerative changes associated with periodontitis in the hippocampus and cerebral cortex. METHODS: Twenty-four Sprague Dawley rats were divided into three groups: Control (n = 8), Ep (n = 8), Ep + Mel (n = 8)…

Circadian rhythm and dietary phytochemicals have emerged as key factors influencing metabolic health and body weight regulation in women. This study aimed to examine the relationship between body weight, circadian rhythm, and dietary phytochemical intake in women. A total of 180 women aged 18 to 65 years participated…

Amaç: Melatonin, sirkadiyen ritmin temel düzenleyicilerinden biri olup psikiyatrik bozukluklarla ilişkili olabileceği düşünülmektedir. Yaygın Anksiyete Bozukluğu (YAB) ile melatonin arasındaki ilişkiye dair bulgular sınırlı ve yöntemsel olarak heterojendir. Bu çalışmada, YAB hastaları ile sağlıklı kontrollerde sabah v…

8575 Background: Although circadian rhythms are known to modulate immune cell function, the effect of immune checkpoint inhibitor (ICI) infusion timing during the day on oncologic outcomes in metastatic non–small cell lung cancer (NSCLC) patients treated with first-line chemoimmunotherapy has not been fully elucidated…

Collective animal behaviors arise from a complex interplay between internal physiological states and external environmental cues. In Caenorhabditis elegans , favorable conditions promote dispersal, while stressors like food scarcity trigger aggregation. Here, we describe a distinct self-organized swarming behavior, wh…

To evaluate the effect of tolterodine and mirabegron on anterior chamber parameters and static pupillometry measurements in overactive bladder (OAB) patients and to compare these results with those of healthy controls. This study included 35 patients with OAB who were planned to be treated with tolterodine, 35 patient…