Systemic Lupus Erythematosus Research

This retrospective study aimed to evaluate sex-related differences in the clinical, laboratory, immunological, and treatment characteristics of patients with systemic lupus erythematosus (SLE) at a single tertiary center. The study included 68 SLE patients (34 females and 34 males) of similar ages at diagnosis, whose…

• BELKIS NİHAN COŞKUN

Aim: This review examines cognitive dysfunctions and their causes in rheumatological diseases on a disease-specific basis. The rheumatological diseases include rheumatoid arthritis, spondyloarthitis, systemic lupus erythematosus, systemic sclerosis, primary sjögren syndrome, fibromyalgia, primary systemic vasculitis,…

Özet henüz yok.

Özet henüz yok.

Objectives To characterize real-world data describing the genetic landscape, clinical phenotype, and outcomes of a monogenic lupus cohort.Methods In this nationwide study, we evaluated all genetically confirmed monogenic lupus patients across Türkiye. Clinical, laboratory, treatment, and outcome data were compared bet…

Systemic sclerosis (SSc) is a complex autoimmune disease characterized by progressive fibrosis, vasculopathy, and multisystem involvement. While clinical assessment appropriately emphasizes measurable outcomes such as organ involvement and survival, these metrics do not fully capture the lived experience of the diseas…

Multiple sclerosis (MS) is a chronic neuroimmunological disorder characterized by inflammation, demyelination, and neuroaxonal loss within the central nervous system. Recent evidence suggests that MS is not only a neuroimmune disease but also associated with systemic metabolic alterations. Furthermore, certain disease…

Özet henüz yok.

Özet henüz yok.

Systemic Lupus Erythematosus (SLE) is a chronic connective tissue disease of unclear etiopathogenesis characterized by affecting multiple organs and systems. Survivin, an apoptosis inhibitor protein (IAP) family member is involved in apoptosis, cell division, development and differentiation. In the pathogenesis of SLE…

Objectives Evidence-based data on the management of thrombocytopenia in systemic lupus erythematosus (SLE) and the platelet threshold for initiating therapy remain limited. This study aimed to evaluate treatment responses in patients with severe immune thrombocytopenia associated with SLE (SLE-ITP) and to assess the i…

Objective: This study aimed to compare the clinical and laboratory characteristics of skin-limited and cutaneous–articular immunoglobulin A vasculitis (IgAV) in children without gastrointestinal or renal involvement, and to assess whether C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and antinuclear…