Vector-borne infectious diseases

Coxiella burnetii is a highly infectious, obligate intracellular Gram-negative bacterium that serves as the primary etiological agent of Q fever, a globally distributed zoonotic disease characterized by its remarkable environmental resilience and its ability to form spore-like small-cell variants that facilitate long-…

Coxiella burnetii is a highly infectious, obligate intracellular Gram-negative bacterium that serves as the primary etiological agent of Q fever, a globally distributed zoonotic disease characterized by its remarkable environmental resilience and its ability to form spore-like small-cell variants that facilitate long-…

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Introduction: Tick salivary glands constitute a largely untapped reservoir of bioactive molecules with significant therapeutic potential. Here, we investigated the selective anticancer activity of salivary gland extract (SGE) from the tortoise tick Hyalomma aegyptium using cancer cell line, non-tumorigenic cells, and…

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease in which host-related factors contributing to disease susceptibility and clinical outcomes remain incompletely understood. We aimed to evaluate the impact of ABO and Rh blood groups on susceptibility and prognosis in patients with CCHF and to investi…

BACKGROUND: In Türkiye, where both Crimean-Congo Hemorrhagic Fever (CCHF) and brucellosis are endemic, these infections share common presenting symptoms, including fever and musculoskeletal complaints, as well as overlapping laboratory findings such as thrombocytopenia and elevated liver enzymes, making early differen…

The biting midge Forcipomyia paludis (Macfie, 1936) is recorded for the first time from Türkiye, based on examined specimens. The species was found in four localities in the European part of the country during 2022 and 2023. Female ectoparasitic specimens were photographed considering their morphological characteristi…

Background and Aim: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by immune dysregulation. Environmental factors, including infectious agents, have been proposed to influence disease activity in inflammatory bowel disease. Although Borrelia burgdorferi has been shown to exert complex im…

Background: Lyme borreliosis is a multisystemic tick-borne infection caused by Borrelia burgdorferi sensu lato complex. Renal involvement is well documented in dogs with Lyme nephritis, whereas human renal manifestations have been reported only rarely, mainly as isolated case reports of glomerular disease. Because a p…

Ticks play an important role in the ecology of zoonotic diseases, however their diversity and host associations in insular ecosystems remain insufficiently documented in Türkiye. We investigated tick occurrence on yellow-legged Gulls (Larus michahellis) and within their nesting environment on Gull Island (Sinop, Türki…

ABSTRACT The segmented genome of Borrelia burgdorferi , the tick-borne agent of Lyme disease, encodes numerous chromosomal and plasmid-borne proteins and small RNAs (sRNAs) of unknown function that are critical for infectivity. Two recent examples are the linear plasmid (lp)17-encoded protein BBD18 and sRNA SR0736 (al…

BackgroundTheileriosis, a tick-borne disease caused by Theileria annulata, leads to global economic losses in livestock, emphasizing an urgent need for the identification of new therapeutic agents with alternative mechanisms of action due to rising buparvaquone resistance combined with climate-driven spread. T. annula…