Bioactive Potential of Six Edible Mushrooms: Antimicrobial, Antioxidant, and Cytotoxic Properties

OpenAlex İngilizce

In the present study, antimicrobial, antibacterial, and cytotoxic effects of methanol and acetone extracts obtained from the edible mushroom species of Boletus edulis, Chanterellus cibarius, Craterellus cornucopioides, Agaricus bisporus, Pleurotus ostreatus, and Morchella esculenta were determined in vitro. The B. edulis methanol extract showed the highest 1,1-diphenyl-2-picrylhydrazy (DPPH) scavenging effect at 1mg mL-1 concentration with 34.68 ± 1.56 %. It was determined that the total phenolic content of the extracts varied between 27.22 ± 2.29 - 16.67 ± 0.88 µg GAE mg-1 extract. The findings suggest that the extracts have varying antimicrobial effects on pathogenic bacteria. 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) cell viability test was performed to investigate the cytotoxic effects of the extracts. Cytotoxicity studies demonstrated that C. cibarius selectively decreased cancer cell viability, while C. cornucopioides, P. ostreatus, and A. bisporus exhibited proliferative effects on cancer cells.