Use of Acti-Heart® in Diagnosis, Follow-Up, and Evaluation of Obesity in Childhood and its Relationship to Other Metabolic Parameters

OpenAlex İngilizce

Objectives: In this study we evaluated changes in lifestyle and motivation, obesity diagnosis, diet and exercise treatments in adolescents using Acti-Heart®, as well as effects on body composition, lipid profile, insulin resistance (IR), adipocytokines, basal metabolic rate and daily calorie consumption. Materials and Methods:A total of 14 cases with an age range of 10.1-16.6 years, and puberty stage of III-IV, who were followed up in our department with a diagnosis of exogenous obesity were included.Thirteen children were included as the control group.Body mass index (BMI), waist and hip circumferences, waist/hip ratio, body fat percentage, skin fold thickness measurements were performed, and glucose, insulin, homeostasis model assessment of IR (HOMA-IR), total cholesterol, low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), triglyceride, serum aspartate and alanin aminotransferase (AST and ALT), visfatin, tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10) and apolipoprotein A (APO A) levels were determined.Calorie consumption was measured using Acti-Heart®.Results: In our patient group, BMI, ALT, glucose, insulin, HOMA-IR, total cholesterol, LDL-C, VLDL-C, triglyceride, visfatin values were high, but TNF-α, IL-10 and APO A levels were low (p<0.05).BMI, waist and hip circumferences, waist/hip ratio, body fat percentage and skin fold thickness decreased in with diet, exercise, and behavioral therapy.HOMA-IR, AST, ALT, VLDL-C, triglyceride, visfatin and hs-C-reactive protein values were also decreased.However, TNF-α, IL-6, and IL-10 levels increased.Daily calorie consumptions measured by Acti-Heart® significantly increased (p=0.004).Conclusion: This is important as it shows increased calorie consumption, parallel changes in body composition, and improvements in metabolic parameters such as decreased VLDL, triglyceride, and IR using Acti-Heart® in obesity treatment monitoring in adolescents.In conclusion, Acti-Heart® is an objective evaluation method for monitoring obesity treatment.The study is planned to be conducted in larger groups of obese children.