Angiosarcoma of the Breast: Case Report

OpenAlex İngilizce

Angiosarcoma is a rare and aggressive tumor of the breast arising from endothelial cells. It is usually associated with chronic lymphedema or radiation therapy. The diagnosis is made by biopsy and there is no specific finding on mammography. In this study, we report a 59-year-old woman with a history of radiotherapy for invasive ductal carcinoma who subsequently developed primary angiosarcoma of the breast. Angiosarcoma of the breast was first documented in 1887 and is classified as primary and secondary. While surgical R0 resection is recommended for the treatment of these tumors with unclear etiology, the significance of axillary lymph node dissection remains uncertain. Adjuvant radiotherapy has been shown to reduce the local recurrence rate, but adjuvant chemotherapy and radiotherapy have no significant effect on 5-year survival. Although there is no consensus on treatment regimens, it is concluded that more comprehensive studies should be conducted in a larger sample.