Makale detayı · 2012 · article
Asymmetric Brønsted Acid Catalyzed Cycloadditions Efficient Enantioselective Synthesis of Pyrazolidines Pyrazolines and 1 3 Diamines from N Acyl Hydrazones and Alkenes
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- YÖKSİSYÖKSİS makale kaydı
- YÖKSİS dergi adıAngewandte Chemie International Edition
- Katalog eşleşmesi (ISSN)Angewandte Chemie - International Edition
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Özet
A general, metal-free, highly enantioselective Brønsted acid catalyzed [3+2] cycloaddition between hydrazones and alkenes has been developed that affords pyrazolidine derivatives (see scheme). The resulting optically active pyrazolidines can undergo many chemical transformations which allow, for example, the enantioselective synthesis of valuable pyrazolines and 1,3-diamines.
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