Evaluation of pediatric prostatic and retroperitoneal embryonal rhabdomyosarcoma with high Ki-67-case series study

OpenAlex İngilizce

However, 11 weeks post-surgery, the patient returned with a recurrent mass.Another surgery was performed to remove the tumor in the left upper thoracic region.Pathology confirmed ERMS with clear surgical margins, with the Ki-67 proliferation index reported at 75%.Immunohistochemical staining also showed positive desmin, SMA, FLI-1, and myogenin results.No fluorodeoxyglucose-18 (FDG) uptake on PET-CT after resection (Figure 1B).Despite complete excision, the patient developed a recurrent tumor protruding from the skin near the vertebral column at the L1-L2 levels, extending toward ABSTRACT Embryonal rhabdomyosarcoma (ERMS) is a highly aggressive pediatric malignancy that can develop in various anatomical locations.This case series presents four pediatric patients diagnosed with ERMS, including one with the uncommon presentation of prostatic rhabdomyosarcoma.By analyzing clinical features, treatment strategies, and outcomes, this study aims to provide insights into the challenges of managing this malignancy in different anatomical sites.