Makale detayı · 2023
SYNTHESIS AND ANTIMICROBIALLY ACTIVITIES OF COUMARIN-3-CARBOXAMIDE DERIVATIVES
YÖKSİS
OpenAlex
Açık erişim · bronze
SJR Q4
JCR Q4
Atıf 5
Yüzdelik 59.6%
FWCI 0.57
- Yıl
- 2023
- ISSN
0035-3930- Tür
- article
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Özet
İngilizce (OpenAlex)
In this study nine coumarin-3-carboxamide derivatives 3a-3i were synthesized with coumarin-3-carboxylic acid chloride and different amines. Two of them, 3c and 3i, are original. The novel substances were purified by column chromatography, and their structures were identified by spectroscopic methods (1H NMR, 13C NMR, IR) and elemental analysis. Coumarin-3-carboxamide derivatives were evaluated antimicrobially against ten different ATTC isolates. The compound 3f was found to be the most effective compound in terms of antibacterial and antifungal activities.
Konular
- Synthesis and biological activity
- Chemical synthesis and alkaloids
- Plant chemical constituents analysis
Birincil konu Synthesis and biological activity