Makale detayı · 2012
Investigation of the in vitro activities of various antibiotics against Brucella melitensis strains
Dergi
TURKISH JOURNAL OF MEDICAL SCIENCES- Yıl
- 2012
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS dergi adı TURKISH JOURNAL OF MEDICAL SCIENCES
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
To assess the antimicrobial susceptibility of Brucella melitensis strains in our region. Brucellosis is a common disease in Turkey. Moreover, difficulties are encountered in the treatment process, such as long-lasting therapy, relapses, and side effects of drugs. Hence, novel treatment approaches and the susceptibility of current antibiotics are vital. Materials and methods: Thirty-four Brucella spp. isolated from blood samples of patients with brucellosis were included. Minimal inhibitory concentrations for tetracycline, rifampicin, streptomycin, ciprofloxacin, doxycycline, ceftriaxone, and levofloxacin were detected by broth microdilution. Results: Tetracycline had the lowest and streptomycin the highest MIC_{50} and MIC_{90} values, respectively. A total of 5 strains were intermediate-susceptible and 1 strain was resistant to rifampicin. Conclusion: Doxycycline and tetracycline seem to be quite effective antibiotics against Brucella melitensis strains. Although streptomycin and rifampicin have high MIC levels against Brucella melitensis strains in our region, inconsistencies between in vitro susceptibility and in vivo activity should be considered.
Konular
Atıflar
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36 atıf
OpenAlex cited_by_count (önbellek / veritabanı)
Yerel katalogda bu makaleye atıf yapan 25 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- In vitro antimicrobial susceptibility of Brucella melitensis isolates from sheep in an area endemic for human Brucellosis in Turkey 2013
- In Vitro Antimicrobial Susceptibility of Brucella melitensis Isolates from Sheep in an Area Endemic for Human Brucellosis in Turkey 2013
- In vitro Antimicrobial Susceptibility of Brucella melitensis Isolates from Sheep in an Area Endemic for Human Brucellosis in Turkey 2013
- Investigation of antibiotic susceptibilities of Brucella Strains isolated from various clinical samples in eastern Turkey 2021
- Investigation of antibiotic susceptibilities of Brucella Strains isolated from various clinical samples in eastern Turkey 2021
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023
- The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged 2023