Makale detayı · 2015 · article
Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens
Veri kaynağı ayrımı
- YÖKSİSYÖKSİS makale kaydı
- YÖKSİS dergi adıCHEMICAL COMMUNICATIONS
- Katalog eşleşmesi (ISSN)Chemical Communications
- OpenAlexOpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
In this study, we designed aptamer-gated nanocapsules for the specific targeting of cargo to bacteria with controlled release of antibiotics based on aptamer-receptor interactions. Aptamer-gates caused a specific decrease in minimum inhibitory concentration (MIC) values of vancomycin for Staphylococcus aureus when mesoporous silica nanoparticles (MSNs) were used for bacteria-targeted delivery.
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Atıflar
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