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akaturk Akademik ölçüm

Makale detayı · 2019

Cytotoxic Activity Studies of Some Platinum (II) Complexes with 2-substitutedbenzimidazole Ligands

Revue Roumaine de Chimie

YÖKSİS OpenAlex Açık erişim · bronze SJR Q4 JCR Q4 Atıf 2 Yüzdelik 7.2% FWCI 0.0
Yıl
2019
ISSN
0035-3930
Tür
article

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  • YÖKSİS YÖKSİS makale kaydı
  • OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)

Özet

İngilizce (OpenAlex)

In the present study, two Pt(II) complexes with 2-substitutedbenzimidazole ligands were synthesized and evaluated for their in vitro cytotoxic activities on HeLa and MCF-7 cell lines.3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test results showed that complex 2 which was found to be the more active than carboplatin was the most cytotoxic active compound against the HeLa and MCF-7 cell lines among the tested compounds.

Konular

  • Synthesis and biological activity
  • Synthesis of Tetrazole Derivatives
  • Synthesis and Characterization of Heterocyclic Compounds

Birincil konu Synthesis and biological activity

Yazarlar

  1. AZİME BERNA ÖZÇELİK GAZİ ÜNİVERSİTESİ
  2. AYSUN KILIÇ SÜLOĞLU HACETTEPE ÜNİVERSİTESİ
  3. GÜLDENİZ SELMANOĞLU HACETTEPE ÜNİVERSİTESİ
  4. FATMA GÜMÜŞ