Makale detayı · 2024
Characterization and genomic analysis of PA-56 Pseudomonas phage from Istanbul, Turkey: Antibacterial and antibiofilm efficacy alone and with antibiotics
YÖKSİS
OpenAlex
Açık erişim · gold
SJR Q1
JCR Q1
Atıf 10
Üst %10
Yüzdelik 91.6%
FWCI 3.22
- Yıl
- 2024
- ISSN
2405-8440- Tür
- article
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- YÖKSİS YÖKSİS makale kaydı
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Özet
İngilizce (OpenAlex)
strains, respectively. PA-56 with strong activity was chosen for detailed characterization, antimicrobial studies, and genome analysis. Combining PA-56 with ciprofloxacin or meropenem demonstrated phage-antibiotic synergism and increased antibiofilm efficacy. Genome analysis revealed a GC ratio of 54 % and a genome size of 42.761 bp, with no virulence or antibiotic resistance genes. Notably, PA-56 harboured the toxin-antitoxin protein, MazG. Overall, this study suggests that PA-56 holds promise for future applications in industry or medicine.
Konular
- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Microbial infections and disease research
Birincil konu Bacteriophages and microbial interactions