Makale detayı · 2005
A Clinico‐pathological Study on the Effect of Vincristine on Transmissible Venereal Tumour in Dogs
Dergi
Zentralblatt für Veterinärmedizin Reihe A- Yıl
- 2005
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS dergi adı Zentralblatt für Veterinärmedizin Reihe A
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
Transmissible venereal tumour (TVT) is a coitally transmitted neoplasm of dogs and is common among sexually active dogs, where sexual behaviour is not under control. Several treatment options are available for the treatment of the tumour, with chemotherapy being the most commonly employed. In this study, we investigated the clinical and cytological changes after weekly vincristine sulphate administration in 38 cases of naturally occurring TVT. Tumours totally regressed in 31 dogs after two to seven doses (mean 3.54 +/- 1.01) of vincristine. One dog died after the fifth dose of vincristine, and in six dogs, an additional treatment with doxorubicin was needed. Masses were still present in four dogs and the histopathological examination revealed small nodules of granulation tissue in two dogs, while viable tumour cells were identified in the remaining two cases. No recurrences were observed in a follow-up period of 7-49 months (mean 13.64 +/- 9.66); in one dog, granulation tissue was detected in the surgery site after 2 months. Treatment success could easily be followed by the cytological changes. In conclusion, vincristine was found to be effective chemotherapeutic agent.
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Atıflar
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Yerel katalogda bu makaleye atıf yapan 15 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors 2017
- Intratumoral recombinant human interferon alpha-2a and vincristine combination therapy in canine transmissible venereal tumour 2018
- Intratumoral recombinant human interferon alpha-2a and vincristine combination therapy in canine transmissible venereal tumour 2018
- Intratumoral recombinant human interferon alpha-2a and vincristine combination therapy in canine transmissible venereal tumour 2018
- Intratumoral recombinant human interferon alpha-2a and vincristine combination therapy in canine transmissible venereal tumour 2018
- Vincristine-associated total antioxidant and oxidant status of ovaries and in vitro nuclear oocyte maturation in dogs with canine transmissible venereal tumor 2023
- Vincristine-associated total antioxidant and oxidant status of ovaries and in vitro nuclear oocyte maturation in dogs with canine transmissible venereal tumor 2023
- Vincristine-associated total antioxidant and oxidant status of ovaries and in vitro nuclear oocyte maturation in dogs with canine transmissible venereal tumor 2023
- Detection of progressive and regressive phase and LINE-1 retrotransposon in transfected dogs with transmissible venereal tumor during chemotherapy 2018
- Detection of progressive and regressive phase and LINE-1 retrotransposon in transfected dogs with transmissible venereal tumor during chemotherapy 2018