Investigation of Changes in Metabolic Parameters and Paraoxonase-1 During the Transition Period in Turkish Saanen Goats

Türkçe

The aim of this study was to evaluate the metabolic changes and PON-1 levels in Turkish Saanen goats during the transition period.In the study, 60 Turkish Saanen goats were used and blood samples were taken from the jugular vein on days -30, -15, 0, +15, and +30 from parturition.In order to monitor metabolic profile changes, alkaline phosphatase (ALP), cholesterol (CHO), glucose (GLU), calcium (CA), phosphorus (PHO), total protein (TOP), triglyceride (TG), paraoxonase-1 (PON-1), β-hydroxybutyric acid (BHBA) and non-esterified fatty acid (NEFA) levels were determined.Serum alkaline phosphatase levels were lower on days -30, 0 and +15, and higher on day +30 (P<0.001).Serum cholesterol and total protein levels were lower on days -30 and 0, and higher on day +30 (P<0.001).Serum levels of glucose, calcium and phosphorus were lower on day 0, and higher on day +30 (P<0.001).Serum triglyceride levels were lower on days -15 and 0, and higher on days -30 and +30 (P<0.05).Serum paraoxonase-1 levels were lower on day 0, and higher on day -30 (P<0.05).Serum β-hydroxybutyric acid levels were lower on day -30, and higher on day +15 (P<0.05).Serum non-esterified fatty acid levels were lower on days -30 and +30, and were higher on days -15 and 0 (P<0.001).In conclusion, the results of our study showed that clear changes in levels of metabolic parameters and PON-1 were seen during the transition period in Turkish Saanen goats.